THE RESULTS OF THE MANTOUX TEST CAN

BE INTERPRETED AS FOLLOWS

1.Negative reaction - complete absence of infiltrate (papule) and hyperemia, a prick reaction of 0 - 1 mm is possible;

2.INDEPENDENT REACTION - infiltrate (papules) 2-4 mm in diameter or hyperemia of any size without infiltrate;

3.POSITIVE REACTION - infiltrate (papules) 5 mm or more in size, as well as vesicles, lymphangiitis, dropouts (several papules of any size around the tuberculin injection site):

mildly positive - papule size 5 - 9 mm;

medium-intensity - papule size 10 - 14 mm;

hyperergic reaction - papule size 17 mm and larger in children and adolescents, 21 mm and larger in adults, as well as vesiculo-necrotic reactions, lymphangiitis, dropouts, regardless of papule size.

A NEGATIVE REACTION TO TUBERCULIN IS CALLED TUBERCULIN ANERGY.

1.FIRST ANERGY - lack of response to tuberculin in uninfected persons.

2.SECONDARY ANERGY - develops in infected people:

•positive secondary anergy - a variant of biological cure of tuberculosis infection or a state of immunoanergy observed, for example, in cases of "latent microbiome";

•negative secondary anergy - in severe forms of tuberculosis.

TUBERCULIN PROVOCATION TESTS:

1.Intradermal test with different dilutions of tuberculin.

2.Koch's subcutaneous tuberculin test.

3.Graded skin test by Grinchar and Karpilovsky (GKP).

4.Tuberculin-fractional examination of erythrocyte sedimentation rate (ESR).

5.The tuberculin-protein Rabukhin-Ioffe test.

6.Eosinophilic-tuberculin test by Mikhailov.

7.Bobrov's haemo-tuberculin test.

4. INSTRUMENTAL RESEARCH

METHODS

1.Radiological DIAGNOSTICS: digital fluorography, tomography, CT scan, radionuclide (scintigraphy), ultrasound (US).

2.BRONCHOLOGICAL DIAGNOSTICS: Bronchoscopy (diagnostic and therapeutic).

3.EXTERNAL Breathing FUNCTION: spirometry (including pneumotachymetry); carbon monoxide (II) diffuse lung capacity assessment - DLCO; total body plethysmography (bodiplegmography); total lung capacity (TLC); lung distensibility (marginal pressure-volume) with food sensing.

4.The 6-Minute Walking Test is an assessment of the patient's functional capacity, especially in the presence of severe and moderate heart and lung pathology.